ProteanFect®高分文献速览：11篇成果覆盖多种原代细胞

题目：CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell exhaustion in colorectal cancer

细胞：小鼠原代CD160⁺ CD8⁺ T细胞

目的：siRNA敲低基因

试剂盒：PT03

题目：Mycobacterium tuberculosis-derived linoleic acid increases regulatory T cell function to promote bacterial survival within macrophages

细胞：小鼠原代CD4+ Treg细胞

目的：siRNA敲低基因

试剂盒：PT03

题目：High fructose consumption aggravates inflammation by promoting effector T cell generation via inducing metabolic reprogramming

细胞：小鼠原代CD4+ T细胞

目的：Cas9 mRNA与sgRNA共转敲除基因

试剂盒：PT06

题目：H2A.Z primes an epigenetic landscape for memory CD8+ T cell recall response

细胞：人原代CD8⁺ T细胞

目的：Cas9 mRNA与sgRNA共转敲除基因

试剂盒：PT05

题目：Spatially resolved multi-omics of human metabolic dysfunction-associated steatotic liver disease

细胞：THP1细胞

目的：siRNA敲低基因

试剂盒：PT01

题目：Phosphorylation of shiftless is important for inhibiting the programmed−1 ribosomal frameshift

细胞：Jurkat细胞

目的：质粒过表达基因

试剂盒：PT01

题目：Ginsenoside F3 alleviates T cell exhaustion via RIPOR2-mediated immunometabolic reprogramming to potentiate anti-PD-1 therapy

细胞：小鼠原代CD8+ T细胞

目的：siRNA敲低基因

试剂盒：PT03

题目：Single-nucleus RNA sequencing illuminates a functional analog of lymphoid organ in crustacean

细胞：Jurkat细胞

目的：质粒过表达基因

试剂盒：PT01

题目：Fatty acid uptake mediated by FABP4 promotes the formation of CD8+T cell senescence through lipid peroxidation in the adipocyte-rich microenvironment of Ovarian Cancer

细胞：小鼠原代CD8+ T细胞

目的：siRNA敲低基因

试剂盒：PT03

题目：Cord blood natural killer cell-derived extracellular vesicles inhibit Zika virus infectivity through ITGB2/perforin-mediated envelope disruption in vitro and in vivo

细胞：脐带血NK细胞

目的：siRNA敲低基因

试剂盒：PT02

题目：Single-round evolution of RNA aptamers with GRAPE-LM

细胞：Jurkat细胞

目的：spCas9-GFP蛋白与sgRNA共转敲除基因

试剂盒：PT08